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Janeway's Immunobiology, by Kenneth Murphy
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Janeway's Immunobiology is a textbook that introduces the immune system in all its aspects to undergraduates, and also provides a treatment of the subject that is comprehensive enough to be useful to graduate students interested in research, and to medical students focused on clinical applications. The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats. Janeway's Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout-that of the host's interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology. Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo. New in the Eighth Edition *Innate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). * The section on complement has been reworked and reconceived-explaining the lectin pathway first-making it easier to teach by placing it into the context of innate recognition. *Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. * The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. * Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. * Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. * Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. * Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. *Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. * The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. * New references have been added throughout the text.
- Sales Rank: #1591972 in Books
- Published on: 2011-08-01
- Format: International Edition
- Original language: English
- Number of items: 1
- Dimensions: 10.98" h x 1.18" w x 8.50" l, .84 pounds
- Binding: Paperback
- 888 pages
Most helpful customer reviews
18 of 18 people found the following review helpful.
An updated classic that doesn't quite live up to its reputation
By a scientist
The original volumes of Janeway were deservedly considered classics. They disrupted the paradigm of texty, word-heavy tomes in favor of refreshingly simple, comprehensive, coherent diagrams. This latest volume does include many of the diagrams I remember but they're no longer central to the text.
I actually read my first copy of Janeway cover to cover in about a week - that's how great it was. I will use this latest version as a reference, but the greatness has been lost under the sheer weight of dry text. This feels like a book that was written by committee with an eye on incorporating information rather than teaching this fascinating subject to eager students.
It's probably still better than most of the other immunology texts out there, but it's no longer an autobuy for me.
15 of 15 people found the following review helpful.
Kindle Version is Pretty Good
By Elgy
There are already many comments on the content, but I wanted to speak to the format of the Kindle Version. First and foremost, the Kindle version is a "print" format which means it will not work on the black-and-white Kindles -- not even the new Kindle Paperwhite. It needs to render images so only the Kindle Fire series, PCs, MACs, and iPad are supported. I don't know why the Android systems are not supported -- it might be a licensing thing.
Even though this textbook is in "print" format, you will still be able to interact with the text -- highlight words, phrases or sentences; use the dictionary; and even add bubble notes.
Zoomed all the way out, the Kindle version looks exactly like the print version. The added features are more like PDF files -- you can do a search, copy text and paste from it, highlight, and as already mentioned, add notes (in a bubble style like in Adobe).
I bought the physical printed version and the Kindle version at the same time...after a few days pondering the pros/cons of print versus ebook, I returned the printed version, and committed to the Kindle version. Since I'm an Android tablet user, I'm tied to my home computer or laptop when I want to read, but this is no major inconvenience.
I have four graduate level classes this semester, and no physical textbooks. This is the lightest my backpack has ever been.
1 of 1 people found the following review helpful.
Serious immunology
By YoYo
Phew! This book is not for the faint-of-heart. I used this as a textbook for an introductory immunology course, and reading each chapter was quite a difficult, but educational, endeavor. I get the feeling that it was designed to be used more as a reference for physicians and immunologists, and it would be good for that purpose since each chapter can stand alone fairly well (in other words, good for the reader who has already taken a good course in immunology). There is tremendous attention to detail with this book. It is very dense, and although there is repetition from chapter-to-chapter (necessary to bring the full picture together), not a sentence is wasted. The figures are consistent and for the most part, well-done.
Immunology is just not an easy subject to present, so I can't fault this book for its presentation of the material. It did just as fine a job of that as I think any book could. I did use a simpler supplemental book to help me understand the subject, which was excellent!! That book is How the Immune System Works, Includes Desktop Edition (Wiley Desktop Editions). If someone is looking to get a more cursory education of the immune system, I would certainly recommend THAT book, and certainly not THIS book.
For what it is though, this is certainly a winner of a textbook.
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